Of the 4,000 Americans waiting for heart transplants, only 2,500 will receive new hearts in the next year. Even for those lucky enough to get a transplant, the biggest risk is their bodies will reject the new heart and launch a massive immune reaction against the foreign cells. To combat the problems of organ shortage and decrease the chance that a patient’s body will reject it, researchers have been working to create synthetic organs from patients’ own cells. Now a team of scientists from Massachusetts General Hospital and Harvard Medical School has gotten one step closer, using adult skin cells to regenerate functional human heart tissue, according to a study published recently in the journal Circulation Research.
Ideally, scientists would be able to grow working hearts from patients’ own tissues, but they’re not quite there yet. That’s because organs have a particular architecture. It’s easier to grow them in the lab if they have a scaffolding on which the cells can build, like building a house with the frame already constructed.
Read more at Popular Science.